(1)Development of the new pretreatment methods for biological sample.
(2)Development of quantitative methods of proteome.
(3)Application of proteomics in cell biology, brain science, public safety and other fields
[1] Yechen Hu, Bo Jiang*, Yejing Weng, Zhigang Sui, Baofeng Zhao, Yuanbo Chen, Lukuan Liu, Qiong Wu, Zhen Liang, Lihua Zhang*, Yukui Zhang, Bis(zinc(II)- dipicolylamine)-functionalized sub-2μm core-shell microspheres for the analysis of N-phosphoproteome, Nature Communications, 2020, 11: 6226
[2] Mingwei Sun, Yu Liang, Yang Li, Kaiguang Yang, Baofeng Zhao, Huiming Yuan, Xiao Li, Xiaodan Zhang, Zhen Liang,?Yichu Shan*,?Lihua Zhang*, Yukui Zhang, Comprehensive Analysis of Protein N-Terminome by Guanidination of Terminal Amines,?Analytical Chemistry, 2020, 92: 567-572.
[3] Kaiguang Yang, Senwu Li, Lukuan Liu, Yuwan Chen, Wen Zhou, Jiaqi Pei, Zhen Liang,?Lihua Zhang*, Yukui Zhang, Epitope Imprinting Technology: Progress, Applications,and Perspectives toward Artificial Antibodies,?Advanced Materials, 2019, 1902048
[4] Jianhui Liu#, Yuan Zhou#, Yichu Shan, Baofeng Zhao, Yechen Hu, Zhigang Sui, Zhen Liang,?Lihua Zhang*, Yukui Zhang, A Multiplex Fragment-Ion-Based Method for Accurate Proteome Quantification,?Analytical Chemistry, 2019, 91: 3921-3928
[5] Qiong Wu#, Bo Jiang#, Yejing Weng, Jianxi Liu, Senwu Li, Yechen Hu, Kaiguang Yang, Zhen Liang,?Lihua Zhang*, Yukui Zhang, 3-Carboxybenzoboroxole Functionalized Polyethylenimine Modified Magnetic Graphene Oxide Nanocomposites for Human Plasma Glycoproteins Enrichment Under Physiological Conditions,?Analytical Chemistry, 2018, 90: 2671-2677
