专家人才库
周雍进 研究员;优青

学历:博士研究生

学科:生物化工

电话:0411-84771060

邮箱:zhouyongjin@dicp.ac.cn

地址:大连市中山路457号

邮编:116023

简历介绍

      周雍进,男,博士,研究员,博士生导师。2006年于江南大学获食品科学与工程学士学位2008 年于天津大学获得生物化工硕士学位;2012年于中国科学院大连化学物理研究所获得生物化工博士学位;2012-2016年在瑞典查尔姆斯理工大学从事博士后研究。2017年引进回到中国科学院大连化物所建立合成微生物学研究组,受聘为研究组组长。曾在CellNature EnergyNature MetabolismNature Chemical BiologyJACSPNASNature Communications等期刊发表论文90余篇。曾获2021年张大煜优秀学者,2018伦世仪教育基金杰出青年学者奖2015年中国药学会科学技术奖一等奖,2016国际代谢科学会议青年科学家奖。

研究方向

  主要研究方向是微生物合成生物学和代谢工程。

      主要研究兴趣为:1)甲醇等一碳资源生物转化;2)微生物细胞反应器构建及优化;3)天然产物生物合成。详情请见课题组主页

职务
社会任职
获奖及荣誉
代表论著

1. Shan Yang, Ruibing Chen, Xuan Cao, Guodong Wang, Yongjin Zhou*, De novo biosynthesis of the hops bioactive flavonoid xanthohumol in yeast, Nature Communications, 2024, 15, 253.

2. Jiaoqi Gao#, Wei Yu#, Yunxia Li, Mingjie Jin, Lun Yao, Yongjin Zhou*, Engineering co-utilization of glucose and xylose for chemical overproduction from lignocellulose, Nature Chemical Biology, 2023, 19, 1524-1531.

3. Xiaoxin Zhai, Jiaoqi Gao, Yunxia Li, Martin Grininger, Yongjin Zhou*, Peroxisomal metabolic coupling improves fatty alcohol production from sole methanol in yeast, Proceedings of the National Academy of Sciences of the United States of America, 2023, 120(12), e2220816120.

4. Min Ye, Jiaoqi Gao, Yongjin Zhou*, Global metabolic rewiring of the nonconventional yeast Ogataea polymorpha for biosynthesis of the sesquiterpenoid β-elemene, Metabolic Engineering, 2023, 76, 225-231.

5. Jiaoqi Gao, Yunxia Li, Wei Yu, Yongjin Zhou*, Rescuing yeast from cell death enables overproduction of fatty acids from sole methanol, Nature Metabolism, 2022, 4, 932-943.

6. Peng Cai, Xiaoyan Wu, Jun Deng, Yongjin Zhou*, Methanol biotransformation toward high-level production of fatty acid derivatives by engineering the industrial yeast Pichia pastoris, Proceedings of the National Academy of Sciences of the United States of America, 2022, 119(29), e2201711119.

7. Ruibing Chen, Jiaoqi Gao, Wei Yu, Xianghui Chen, Xiaoxin Zhai, Yu Chen, Lei Zhang*, Yongjin Zhou*, Engineering cofactor supply and recycling to drive phenolic acid biosynthesis in yeast. Nature Chemical Biology, 2022, 18(5), 520-529.

8. Peng Cai#, Xingpeng Duan#, Xiaoyan Wu, Linhui Gao, Min Ye, Yongjin Zhou*, Recombination machinery engineering facilitates metabolic engineering of the industrial yeast Pichia pastoris. Nucleic Acids Research, 2021, 49(13), 7791–7805

9. Tao Yu#, Yongjin Zhou#, Mingtao Huang, Quanli Liu, Rui Pereira, Florian David, Jens Nielsen*, Reprogramming yeast metabolism from alcoholic fermentation to lipogenesis. Cell. 2018, 174(6), 1549-1558.

10. Yongjin Zhou, Eduard Kerkhoven, Jens Nielsen*, Barriers and opportunities in bio-based production of hydrocarbons. Nature Energy, 2018, 3, 925-935.


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