(1) Development of high-throughput proteome sample treatment device
(3) Development of new methods for large-scale preparation of high-purity exosomes towards clinical applications
[1] Huiming Yuan*, Zhongpeng Dai, Xiaodan Zhang, Baofeng Zhao, Hongwei Chu, Lihua Zhang*, Yukui Zhang, Fully automated sample treatment method for high throughput proteome analysis, Science China-Chemistry, 2021, 64, 313-321.
[2] Yilan Li, Huiming Yuan*, Zhongpeng Dai, Weijie Zhang, Xiaodan Zhang, Baofeng Zhao, Zhen Liang, Lihua Zhang*, Yukui Zhang, Integrated proteomic sample preparation with combination of on-line high-abundance protein depletion, denaturation, reduction, desalting and digestion to achieve high throughput plasma proteome quantification. Anal. Chim. Acta. 2021, 1154, 338343.
[3] Qiong Wu, Baofeng Zhao, Yejing Weng, Yichu Shan, Xiao Li, Yechen Hu, Zhen Liang, Huiming Yuan*, Lihua Zhang*, Yukui Zhang, Site-Specific Quantification of Persulfidome by Combining an Isotope-Coded Affinity Tag with Strong Cation-Exchange-Based Fractionation, Analytical Chemistry, 2019, 91, 14860-14864.
[4] Huiming Yuan, Bo Jiang, Baofeng Zhao, Lihua Zhang*, Yukui Zhang, Recent Advances in Multidimensional Separation for Proteome Analysis, Analytical Chemistry, 2019, 91, 264-276.
[5] Shen Zhang# , Huiming Yuan#, Baofeng Zhao, Lihua Zhang*, Yukui Zhang, Integrated platform with combination of on-line protein digestion, isotope dimethyl labeling and multidimensional peptide separation for high-throughput proteome quantification, Analytica Chimica Acta, 2018, 1000,172-179.