(1) Microfludics-based single-cell analysis technology and its biomedical applications.
(2) Digital microfluidic system.
Representative Books:
[1] Biosensors For Single-cell Analysis. Chen Jian, Yao Lu. 2021, United Kingdom: Academic Press.
[2] Organ on a Chip, Bingcheng Lin, Yong Luo, Tingjiao Liu, Yao Lu, 2019, Science Press.
Representative Punlications:
1. Linmei Li#; Haoran Su#; Yahui Ji; Fengjiao Zhu; Jiu Deng; Xue Bai; Huibing Li; Xianming Liu; Yong Luo; Bingcheng Lin; Tingjiao Liu*; Yao Lu*; Deciphering Cell–Cell Interactions with Integrative Single‐Cell Secretion Profiling, Advanced Science, 2023, 2301018.
2. Huibing Li; Xianming Liu*; Fengjiao Zhu; Dachuan Ma; Chunyue Miao; Haoran Su; Jiu Deng; Haiyue Ye; Hongyu Dong; Xue Bai; Yong Luo; Bingcheng Lin; Tingjiao Liu*; Yao Lu*; Spatial barcoding-enabled highly multiplexed immunoassay with digital microfluidics., Biosensors and Bioelectronics, 2022, 215: 114557.
3. Jiu Deng; Yahui Ji; Fengjiao Zhu; Lina Liu; Linmei Li; Xue Bai; Huibing Li; Xianming Liu; Yong Luo; Bingcheng Lin; Yao Lu*; Mapping secretome-mediated interaction between paired neuron–macrophage single cells, PNAS, 2022, 119(44): 1-11.
4. Yahui Ji, Dongyuan Qi, Linmei Li, Haoran Su, Xiaojie Li, Yong Luo, Bo Sun, Fuyin Zhang, Bingcheng Lin, Tingjiao Liu*, Yao Lu*; Multiplexed profiling of single-cell extracellular vesicles secretion, PNAS, 2019, 116(13): 5979-5984.
Yao Lu#, Qiong Xue#, Markus Eisele, Endah Sulistijo, Kara Brower, Lin Han, El-ad David Amir, Dana Pe’er, Kathryn Miller-Jensen* & Rong Fan*; Highly multiplexed profiling of single-cell effector functions reveals deep functional heterogeneity in response to pathogenic ligands, PNAS, 2015, 112(7): E607-E615.